The association of spinal morning stiffness with lumbar disc degeneration and C-reactive protein: The back complaints in older adults (BACE) study.

ABSTRACT:

Objective

To determine the association between patient-reported spinal morning stiffness and lumbar disc degeneration (LDD) and systemic inflammation, as measured by C-reactive protein (CRP), in older patients with non-specific back pain. The ultimate objective is to help shape a future definition of spinal osteoarthritis (OA).

Design

Baseline data from the Dutch "Back Complaints in the Older Adults" (BACE) study was used. The relationship between the severity and duration of patient-reported spinal morning stiffness, LDD (i.e., multilevel disc space narrowing and multilevel osteophytes), and CRP was assessed. Regression models adjusted for confounding variables were performed.

Results

Six hundred and seventy-five patients were included. The mean age was 66.52 years (

SUBMITTER: Feller D 

PROVIDER: S-EPMC11566339 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature