A polymer deposition-mediated surface-charge reformation strategy: reversing the MOF biomineralization behavior.

ABSTRACT: Biomineralization of a porous metal-organic framework (MOF) shell onto biomacromolecule templates is a burgeoning strategy to construct robust biocatalysts. However, it strongly relies on the interfacial interaction between MOF precursors and enzyme surface, significantly limiting the generalization of this nanotechnology. Herein, we identify polymers that are well-suited for deposition onto target biomacromolecules via supramolecular interactions and introduce a polymer deposition-mediated surface-charge reformation strategy to facilitate the biomineralization of porous MOFs, including ZIF-8, ZIF-90, and ZIF-zni onto enzymes. We investigate nine commercially available polymers to find that those with dense -SO₃H and -COOH groups effectively regulate the surface-charge pr

SUBMITTER: Xu Y 

PROVIDER: S-EPMC11575559 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature