The relationship between serum alpha-klotho levels and urinary incontinence in middle-aged and older females: insights from NHANES.

ABSTRACT: Urinary incontinence (UI) in females is a prevailing condition that affects individuals across various age groups and is not limited to older females. The presence of serum alpha-Klotho (α-klotho) serves as a reliable biomarker to indicate the effects of antiaging. Nevertheless, the scientific research on the association between α-klotho and UI remains limited. Therefore, the purpose of this study is to investigate and evaluate the connection between α-klotho levels and the UI among females in the US. We utilized data from the National Health and Nutrition Examination Survey 2007-2016 to investigate the potential connection between α-klotho levels and the UI among females aged 40 to 79. Weighted linear regression models and sensitivity tests were conducted to explore the correlation. 2628

SUBMITTER: Tang X 

PROVIDER: S-EPMC11577013 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature