Clinical and cognitive features associated with psychosis in Parkinson's disease: a longitudinal study.

ABSTRACT:

Background

Parkinson's disease psychosis (PDPsy) is associated with increased nursing home placement and mortality and is closely linked with cognitive dysfunction.

Objective

Assess the clinical and cognitive features associated with PDPsy in patients without dementia.

Methods

We prospectively recruited people with Parkinson's disease (PwP) without dementia for a 3-year, longitudinal study at an outpatient movement disorders clinic. Participants completed annual visits involving assessment of motor and non-motor symptoms including neuropsychological testing. PDPsy was defined as the recurring presence of visual illusions, sense of presence, hallucinations, or delusions for at least 1 month. Using generalized estimating equations, we conducted two sets of analyses to s

SUBMITTER: Flanigan JL 

PROVIDER: S-EPMC11579864 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature