Determinants of long-term survival in patients with IDH-mutant gliomas.

ABSTRACT:

Background

Survival times of patients with IDH-mutant gliomas are variable and can extend to decades. Many studies provide progression-free rather than overall survival times and prognostic factors remain ill-defined. Here we explored characteristics of short- and long-term survivors within a cohort of patients with extended follow-up.

Methods

This single-center, case-control study included 86 patients diagnosed between 1998 and 2023 who either died within 6 years after diagnosis or survived at least 15 years. Patient characteristics and prognostic factors were stratified by short- (< 6 years) versus long-term (≥ 15 years) survival.

Results

Forty-seven patients (55%) diagnosed with astrocytoma and 39 patients (45%) with oligodendroglioma were included retrospectively.

SUBMITTER: Katzendobler S 

PROVIDER: S-EPMC11614945 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature