A feasibility study of using virtual noncontrast images synthesized from dual-energy computed tomography for radiotherapy treatment planning.

ABSTRACT:

Background

In the traditional computed tomography (CT) simulation process, patients need to undergo CT scans before and after injection of iodine-based contrast agent, resulting in a cumbersome workflow and additional imaging dose. Contrast-enhanced spectral CT can synthesize true contrast-enhanced (TCE) images and virtual noncontrast (VNC) images in a single scan without geometric misalignment. To improve work efficiency and reduce patients' imaging dose, we studied the feasibility of using VNC images for radiotherapy treatment planning, with true noncontrast (TNC) images as references and explored its dosimetric advantages compared to using TCE images. Specifically, this study examined tumors near bones, including cases of bone metastasis and myeloma.

Methods

A total of 54

SUBMITTER: Wei S 

PROVIDER: S-EPMC11652005 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature