Genome-Wide Analysis of the Metallocarboxypeptidase Inhibitor Family Reveals That AbMCPI8 Affects Root Development and Tropane Alkaloid Production in Atropa belladonna.

ABSTRACT: Atropa belladonna is a medicinal plant and an important source for the commercial production of tropane alkaloids (TAs), such as scopolamine and hyoscyamine, which are used clinically for their anticholinergic properties. In this study, we identified 16 metallocarboxypeptidase inhibitor (MCPI) genes from A. belladonna (AbMCPIs), which are grouped into three subgroups based on phylogenetic relationships and are distributed across 10 chromosomes. Promoter analysis showed that most cis-regulatory elements were related to defense and stress responses, such as drought, low-temperature, ABA (abscisic acid), GA (gibberellin), auxin, light and MeJA responsiveness. A gene encoding a putative metallocarboxypeptidase inhibitor (AbMCPI8) is cloned from A. belladon

SUBMITTER: Yang S 

PROVIDER: S-EPMC11676366 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature