Dataset Information

Associations Between Dry Eye Disease and Mental Health Conditions in the All of Us Research Program.

ABSTRACT:

Purpose

To determine the association between dry eye disease (DED) and mental health conditions in a sociodemographically diverse nationwide population of Americans.

Design

Cross-sectional study.

Methods

We used the National Institute of Health's All of Us Research Program database to identify 18257 participants with DED who were propensity score matched in a 1:3 ratio to participants without DED. Univariate and multivariable logistic regression models were used to assess associations between DED and mental health conditions (i.e., depressive disorders, anxiety, bipolar disorder, and schizophrenic spectrum disorder).