Coagulation and platelet function in cold-stored whole blood on missions in a helicopter emergency service.

ABSTRACT:

Background

Haemorrhage is a leading cause of morbidity and mortality in trauma, and prehospital transfusion of blood products is often necessary. Whole blood has been proposed to be the best alternative, but it is unclear whether, and how, storage and transport of the blood in a helicopter affects the blood units. We investigated the coagulation capacity and platelet function in whole blood at different time points during helicopter missions.

Methods

Twenty units of low-titre group O RhD negative whole blood were collected from healthy volunteers and analysed before, during and after transport in a helicopter. Coagulation and platelet function, as measured by thromboelastography, and blood samples for pH, electrolytes, glucose and lactate were assessed at baseline and 24, 72

SUBMITTER: Sato Folatre JG 

PROVIDER: S-EPMC11744058 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature