Yield and clinical impact of image-guided bone biopsy in osteomyelitis of the appendicular skeleton: a systematic review and meta-analysis.

ABSTRACT:

Objective

To assess the yield and clinical impact of image-guided bone biopsy for osteomyelitis of the appendicular skeleton.

Materials and methods

A literature search of several databases was conducted from inception to August 2023. Eligible studies reported patients who underwent image-guided bone biopsy for investigation of osteomyelitis of the appendicular skeleton. The pooled proportions were analyzed using a random-effects model. This review was registered in PROSPERO (CRD42023466419).

Results

From 370 initial studies screened, eight met the eligibility criteria, with a total of 700 patients. The pooled technical success rate was 99.6% (95% CI: 0.992, 1.001; I² = 0%). Positive bone cultures were pooled at 31.9% (95% CI: 0.222, 0.416; I² = 8

SUBMITTER: Smayra K 

PROVIDER: S-EPMC11769862 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature