Multiorgan Dysfunction and its Association With Congestion and Outcome in Aortic Stenosis Treated With TAVI.

ABSTRACT:

Background

Degenerative severe aortic stenosis (AS) is treated by valve replacement to improve outcome. Despite diagnostic advancements, many AS patients are still diagnosed late with advanced heart failure.

Objectives

The aim of the study was to assess multiorgan dysfunction in severe AS using blood biomarkers and their association with quantitative fluid levels and clinical outcomes after transcatheter aortic valve implantation (TAVI).

Methods

Consecutive AS patients undergoing TAVI received comprehensive preinterventional assessment with serum biomarker profiles reflecting organ dysfunction and quantitative fluid overload (FO) using bioelectrical impedance spectroscopy. FO by bioelectrical impedance spectroscopy was defined according to a previously established cut

SUBMITTER: Halavina K 

PROVIDER: S-EPMC11780109 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature