Multicentre case-control study on the association between COVID-19 vaccines and neurological disorders (COVIVAX).

ABSTRACT: The COVIVAX study assessed the association between COVID-19 vaccination and the risk of common neurological disorders in a multicenter case-control design. Vaccination exposure was compared between individuals with a first diagnosis of a neurological disorder (cases) and age- and sex-matched controls. A total of 624 participants were enrolled, and after random 1:1 matching 265 cases and 265 matched controls (total 530 participants) were included in the analyses. The most frequent neurological diagnosis in cases were stroke (60.4%), multiple sclerosis (11.3%) and seizures (6.4%). The proportion of vaccinated participants was 72.1% among cases and 79.6% among controls. A protective role of vaccination on the risk of developing a new neurological disorder was detected in the unadjusted analys

SUBMITTER: Pupillo E 

PROVIDER: S-EPMC11794632 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature