Structural brain changes in post-COVID condition and its relationship with cognitive impairment.

ABSTRACT: It has been estimated that ∼4% of individuals infected with SARS-CoV-2 will be diagnosed with post-COVID condition. Previous studies have evidenced the presence of cognitive dysfunction and structural brain changes in infected individuals; however, the relationship between structural changes and cognitive alterations in post-COVID condition is still not clear. Consequently, the aim of this work is to study structural brain alterations in post-COVID condition patients after almost 2 years of infection and their likely relationship with patients' cognitive impairment. Additionally, the association with blood biomarkers and clinical variables was also explored. One hundred and twenty-eight individuals with post-COVID condition and 37 non-infected healthy controls from the Nautilus Project (Cl

SUBMITTER: Pacheco-Jaime L 

PROVIDER: S-EPMC11851114 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature