Multicomponent Interventions for Adults With Cancer Cachexia: A Systematic Review.

ABSTRACT:

Background

Cancer cachexia has substantial impacts on people's quality of life. There is no current gold standard treatment, but the complex pathophysiology of cachexia suggests that a multitargeted and individualised treatment approach is needed. We aimed to evaluate the extent to which multicomponent interventions have targeted the key features of cachexia and been tailored to individuals, and differential effects on quality of life.

Methods

We conducted a systematic review of multicomponent interventions for adults with cancer cachexia. We searched four databases, two clinical trial registers and MedRxiv on 20 June 2024. Intervention components were classified by intervention category (nutritional, exercise/physical activity, pharmacological and psychosocial), cachexia fe

SUBMITTER: Bowers M 

PROVIDER: S-EPMC11865637 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature