Impulse control deficits among patients with nonsuicidal self-injury: a mediation analysis based on structural imaging.

ABSTRACT:

Background

Nonsuicidal self-injury (NSSI) is posited to arise from a complex interaction of biopsychosocial factors, with impulsivity playing a critical role. Given that current research on the neural mechanisms underlying this hypothesis remains inconsistent and limited in scope, we sought to explore how NSSI behaviours are associated with impulsivity resulting from structural brain alterations.

Methods

We recruited patients with NSSI behaviours and healthy controls from 11 psychiatric hospitals. We assessed the differences in impulse control between the 2 groups using the Barratt Impulsiveness Scale version 11 and the Attention Network Test. We also conducted T ₁-weighted magnetic resonance imaging (MRI) and diffusion tensor imaging. Finally, we analyzed

SUBMITTER: Xie Y 

PROVIDER: S-EPMC11882201 | biostudies-literature | 2025 Mar-Apr

REPOSITORIES: biostudies-literature