Association of estimated glomerular filtration rate with the incidence of sleep apnea syndrome.

ABSTRACT:

Study objectives

Sleep apnea syndrome (SAS) is potentially linked to life-threatening conditions. The decline in kidney function is involved in the development of various diseases; however, it remains unclear whether it is implicated in the onset of SAS. Therefore, this study aimed to investigate the relationship between kidney function and the incidence of SAS.

Methods

The association of estimated glomerular filtration rate (eGFR) with the incidence of SAS was assessed retrospectively using real-world administrative claims and health checkup data collected between April 2014 and November 2022. To strengthen robustness, three stratified analyses and four sensitivity analyses were conducted.

Results

We assessed 1 589 259 individuals for the analysis. During a median (i

SUBMITTER: Azegami T 

PROVIDER: S-EPMC11893532 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature