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An adaptive, continuous substrate feeding strategy based on evolved gas to improve fed-batch ethanol fermentation.


ABSTRACT: Advances in the ethanol fermentation process are essential to improving the performance of bioethanol production. Fed-batch fermentation is a promising approach to increase the final ethanol titer, which benefits the recovery in the bioethanol industry's downstream process. However, the development of feeding strategies, a crucial control variable in the fed-batch approach, is limited. Thus, in the present work, different modes of substrate delivery-fixed feeding, adapted feeding-were investigated in fed-batch cultures of Saccharomyces cerevisiae in a 5-L bioreactor. Evolved gas production, which was positively correlated with glucose consumption, was used to adjust the sugar feed rate in fed-batch fermentations under an adapted feeding strategy. The adapted feeding strategy enhanced ethan

SUBMITTER: Hung YR 

PROVIDER: S-EPMC11903602 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature