Characterization of insecticide resistance mechanisms in the Anopheles gambiae population of Sierra Leone.

ABSTRACT:

Background

Information on the status of insecticide resistance in malaria vectors is critical for implementing effective malaria vector control. The Sierra Leone National Malaria Control Programme, in collaboration with the PMI VectorLink project, assessed the resistance status to insecticides commonly used in public health, and associated resistance mechanisms in Anopheles gambiae, the main vector of malaria in Sierra Leone.

Methods

The susceptibility of An. gambiae against pyrethroids with and without piperonyl butoxide (PBO), chlorfenapyr, clothianidin, bendiocarb and pirimiphos-methyl was evaluated in four districts of Sierra Leone in 2018 and 2019 using WHO and CDC bottle bioassay protocols. A subset of samples that were exposed to the insecticides were screened for mol

SUBMITTER: Opondo KO 

PROVIDER: S-EPMC11907884 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature