Lignan Intake and Mortality Among Adults with Incident Type 2 Diabetes-Prospective Cohort Studies.

ABSTRACT:

Background

Lignans are polyphenolic compounds abundant in plant-based foods such as seeds, whole grains, and certain fruits and vegetables and may lead to favorable metabolic health. It remains to be elucidated regarding the role of lignan consumption in the etiology of premature deaths among individuals with diabetes.

Objectives

To prospectively examine the association between postdiagnosis lignan intake and mortality among individuals with type 2 diabetes (T2D).

Methods

We analyzed data from 2 prospective United States cohorts, the Nurses' Health Study (1984-2020) and Health Professionals Follow-up Study (1986-2022). Mean daily consumption of total and individual lignans was calculated, and postdiagnosis lignan intakes were cumulatively averaged. Multivariable-adjus

SUBMITTER: Liu B 

PROVIDER: S-EPMC11923372 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature