Lettuce fortification through vitamin B₁₂-producing bacteria - proof of concept study.

ABSTRACT:

Background

Vitamin B₁₂ (cobalamin) can be produced de novo only by certain bacteria and archaea. It plays a crucial role in the health of animals and humans, which obtain it only through diet, mainly from animal products. This study aimed to identify endophytic bacterial strains capable of synthesizing vitamin B₁₂ and enriching edible plants with it as a potential solution for vitamin B₁₂ deficiency in vegetarians, vegans, and people with poor diets.

Results

An in silico genome analysis was performed on 66 bacterial genomes, including the reference strain Pseudomonas denitrificans ATCC 13867, a known vitamin B₁₂ producer. The genomes were analyzed using the Rapid Annotations using Subsystems Technology (RAST) server and the MetaCyc

SUBMITTER: Pipponzi S 

PROVIDER: S-EPMC11949862 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature