Genetically Engineered Hypoimmune Human Muscle Progenitor Cells Can Reduce Immune Rejection.

ABSTRACT: Cells face two challenges after transplantation: recognition and killing by lymphocytes, and cell apoptosis induced by the transplantation environment. Our hypoimmune cells aim to address these two challenges through editing of immunomodulatory proteins and overexpression of anti-apoptotic proteins.

SUBMITTER: Chen Y 

PROVIDER: S-EPMC11969239 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature