Risk factors and outcomes of pediatric non-invasive respiratory support failure in Latin America.

ABSTRACT:

Background

Noninvasive respiratory support (NRS) is standard in pediatric intensive care units (PICUs) for respiratory diseases, but its failure can lead to complications requiring invasive mechanical ventilation (IMV). This study aimed to identify risk factors for NRS failure in children with acute respiratory failure (ARF) in PICUs, and compare complications and outcomes between IMV-only and NRS failure patients.

Methods

We conducted a cohort study using data from the LARed Network prospective registry (April 2017-November 2022), in children under 18 years admitted to PICUs for ARF. Cases were divided into subgroups: those managed with IMV only, those who experienced NRS failure requiring IMV, those who received NRS successfully, and those who did not require NRS or IMV. E

SUBMITTER: Escobar-Serna DP 

PROVIDER: S-EPMC11997567 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature