Effects of dietary interventions for metabolic acidosis in chronic kidney disease: a systematic review and meta-analysis.

ABSTRACT:

Background

Metabolic acidosis is a common complication of kidney disease and can result in further disease progression. Alkali therapy has been used to treat metabolic acidosis for decades. However, some concerns have been raised regarding its safety and long-term tolerability. Existing data suggest that dietary interventions can be beneficial in the management of chronic kidney disease (CKD). This systematic review and meta-analysis aims to summarize findings from studies comparing dietary interventions with placebo/usual care/no treatment in the management of metabolic acidosis in outpatient adults with CKD.

Methods

Medline, Embase, Cochrane Central, CINAHL and Web of Science Core Collection were searched from inception to June 2022. Our primary outcome measure was change

SUBMITTER: Mahboobi S 

PROVIDER: S-EPMC11997807 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature