Magnetic scaffolds for the mechanotransduction stimulation in tendon tissue regeneration.

ABSTRACT: Nowadays, tendon injuries represent a global health issue that annually affects millions of individuals. An innovative approach for their treatment is represented by the development of tissue engineered scaffolds able to support the host cells adhesion, differentiation, and proliferation. However, the scaffold alone could be insufficient to guarantee an improvement of healing control. Magnetite nanoparticles (Fe₃O₄ NPs) are gaining interest due to their unique properties. In particular, when combined with bio-mimetic scaffolds, they should lead to the cells mechano-stimulation, improving the tenogenic differentiation and allowing a deeper tissue reparation. The aim of this work is the study and the development of scaffolds based on polyhydroxybutyrate and gelatin and

SUBMITTER: Bianchi E 

PROVIDER: S-EPMC11999374 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature