Association of Perioperative Glucagon-like Peptide-1 Receptor Agonist Use and Postoperative Outcomes.

ABSTRACT:

Objective

To assess rates of surgical complications and postoperative readmission in diabetic patients with and without active perioperative prescriptions for glucagon-like peptide-1 receptor agonist (GLP-1 RA) medications.

Background

With the rapid growth of GLP-1 RA use in the United States, it is important to understand the potential effect of these drugs on surgical outcomes broadly.

Methods

In this retrospective, observational cohort analysis, patients with a diagnosis of type 1 or type 2 diabetes undergoing a surgical procedure at a multicenter quaternary-care health care system between February 2020 and July 2023 were included. Propensity score matching was performed between procedures in patients with and without an active GLP-1 RA prescription. The primary ou

SUBMITTER: Aschen SZ 

PROVIDER: S-EPMC12014183 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature