The complete genome sequence of the crayfish pathogen Candidatus <i>Paracoxiella cheracis</i> n.g. n.sp. provides insight into pathogenesis and the phylogeny of the Coxiellaceae family.

ABSTRACT: The Coxiellaceae bacterial family, within the order Legionellales, is defined by a collection of poorly characterized obligate intracellular bacteria. The zoonotic pathogen and causative agent of human Q fever, Coxiella burnetii, represents the best-characterized member of this family. Coxiellaceae establish replicative niches within diverse host cells and rely on their host for survival, making them challenging to isolate and cultivate within a laboratory setting. Here, we describe a new genus within the Coxiellaceae family that has been previously shown to infect economically significant freshwater crayfish. Using culture-independent long-read metagenomics, we reconstructed the complete genome of this novel organism and demonstrate that the species previously referred to as Candid

SUBMITTER: Ingle DJ 

PROVIDER: S-EPMC12039232 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature