Splenic comparative transcriptome analysis reveals the immunological mode of undomesticated Gayal (Bos frontalis) for adapting to harsh environments.

ABSTRACT:

Background

The utilization of transcriptome technology in the identification of pivotal regulatory genes associated with immunity is of paramount importance. Previous studies have shown that undomesticated gayal (Bos frontalis) may have higher humoral responses which is comparable to yaks. However, research on immune function of gayal is limited, and comparisons with different breeds are rarely reported. The objective of this study was to inspect the immune status and compare splenic differential expression genes (DEGs) through comparative transcriptome analysis of gayal and domesticated local cattle (Yunan yellow cattle).

Results

Serum immunological status investigation showed the better humoral immune status and lower levels of pro-inflammatory cytokines of gayal when comp

SUBMITTER: Yu Y 

PROVIDER: S-EPMC12093757 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature