Increased expression of <i>RIPOR1</i> predicts the poor prognosis of colorectal cancer patients.

ABSTRACT:

Background

Colorectal cancer (CRC) is considered one of the main causes of cancer-related deaths. Rho family-interacting cell polarization regulator 1 (RIPOR1) is a new Rho effector protein, and its abnormal expression may be related to various tumors. However, its expression and significance in CRC are still unclear. We aimed to explore its role and potential value in CRC, and to provide a new theoretical basis of prognostic evaluation and targeted therapy for CRC patients.

Methods

Here we investigated the expression and significance of RIPOR1 from public databases by using bioinformatics methods. Immunohistochemistry (IHC) was performed to determine protein expression levels of RIPOR1 in CRC patients, and the correlation between RIPOR1 expressio

SUBMITTER: Yue X 

PROVIDER: S-EPMC12170205 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature