Genomic and phylogeographical analysis revealed CTX-M-55 producing <i>Escherichia coli</i> ST10 and ST2325 clones of One Health concern from dairy farm waste in Gansu, China.

ABSTRACT: Extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli resists broad-spectrum cephalosporins, considered as a critical priority pathogen, and its presence in animals, humans, and the environment highlights its significance as a One Health issue. Dairy farm waste is a potential environmental contaminant and can serves as a significant reservoir for the emergence and spread of ESBL-producing E. coli, which belongs to One Health clones and poses a serious global threat. This study aimed to investigate the occurrence and genomic characteristics of ESBL-producing E. coli clones of One Health concern from dairy farm waste in Gansu, China. In this study, we isolated and characterized two CTX-M-55 ESBL-producing E. coli strains, ZYX8158 and ZYS8091, which be

SUBMITTER: Shoaib M 

PROVIDER: S-EPMC12179727 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature