Impact of automated insulin delivery on subjective and objective sleep in children and young adults with very high HbA1c: Sleep outcomes from the CO-PILOT randomised controlled trial.

ABSTRACT:

Aims

To assess how automated insulin delivery (AID) impacts sleep in young people with type 1 diabetes and suboptimal glycaemia (HbA1c ≥ 69 mmol/mol).

Methods

We conducted a randomised controlled trial comparing AID to usual care in 80 participants (aged 7-25 years) over 13 weeks. Sleep was a secondary outcome assessed at baseline and 13 weeks using questionnaires (subjective) and accelerometry (objective).

Results

All participants completed the trial; 64 provided subjective and 40 provided objective sleep data. Participants reported poor subjective sleep quality alongside high levels of sleep disturbance and sleep-related impairment at both timepoints. At 13 weeks, sleep-related impairment improved more in the intervention group than in controls (MD = -4.7; 95% CI = 

SUBMITTER: Michaels VR 

PROVIDER: S-EPMC12257429 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature