A novel approach for the identification of cadmium-chelating compounds in plant-based foods using SEC-ICP-MS/MS and SEC-QTOF-MS.

ABSTRACT: The increasing trend towards more plant-based diets has underscored the need for a comprehensive understanding of the presence of potentially toxic elements in plant-based foods. Among these, cadmium is of particular concern due to its potential health risks. Our understanding of how cadmium is bound in plant-based foods and how this affects its bioavailability is currently limited. This paper introduces a qualitative methodology that combines SEC-ICP-MS/MS and SEC-QTOF-MS for identifying cadmium-chelating compounds and performing simultaneous speciation analysis of phosphorus, sulfur, calcium, iron, and zinc in plant-based foods. The present study details the optimization of the cadmium extraction process across seven different matrices with varying protein content. A large variation in t

SUBMITTER: Cardini J 

PROVIDER: S-EPMC12276129 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature