Association between Cognitive Frailty and Adverse Outcomes among Older Adults: A Meta-Analysis.

ABSTRACT:

Objectives

This systematic review and meta-analysis aimed to pool the effect size of the association between cognitive frailty and adverse outcomes (e.g., falls, disability, and hospitalization) among older adults.

Design

Systematic review and meta-analysis.

Methods

PubMed, ScienceDirect, and Embase were searched from their respective inceptions to June 1, 2022. We extracted prospective cohort studies that reported the association between cognitive frailty and adverse outcomes. Random or fixed-effects models based on heterogeneity were used to pool the effect sizes of independent associations of cognitive frailty, frailty only, and cognitive impairment only with each adverse outcome.

Results

Fifteen studies involving 49,122 older adults were included in the met

SUBMITTER: Zhang XM 

PROVIDER: S-EPMC12280716 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature