Comparative efficacy of conservative interventions for adolescent idiopathic scoliosis: a systematic review and network meta-analysis of randomized controlled trials.

ABSTRACT:

Background

Adolescent idiopathic scoliosis (AIS) is a prevalent spinal disorder, and the efficacy of conservative interventions for AIS remains unclear. This study aimed to identify the comparative efficacy of all available conservative interventions for AIS.

Methods

Nine databases were searched from their inception to February 2024 for randomized controlled trials comparing conservative interventions for AIS. Paired reviewers independently selected studies, assessed risk of bias, and assessed certainty of the evidence. Pairwise meta-analyses were performed by DerSimonian-Laird random-effects model. Network meta-analysis within the frequentist framework was conducted by R package netmeta, and network plots were generated by the network plot command in Stata.

Results

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SUBMITTER: Ren J 

PROVIDER: S-EPMC12309149 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature