Direct Surface Modification of the Epidermis Using Mussel-Inspired Polydopamine with Multiple Anti-Biofouling Functions.

ABSTRACT: The surface properties of the epidermis are crucial in pathogen adhesion and proliferation. Moreover, damage to the epidermis caused by various physical and chemical attacks provides a favorable environment for pathogen penetration and proliferation through the exposed internal living tissue. Surface modification of the epidermis to impart anti-biofouling properties can provide effective protection against infections. In this study, a facile method of imparting multiple anti-biofouling functions by directly modifying the epidermal surface of an organism using dopamine, which is a mussel-inspired substance, is introduced. Biocompatible polydopamine (PDA) is uniformly applied to organic surfaces with diverse morphological features and surface energies, indicating its versatility. In addition

SUBMITTER: Lee SE 

PROVIDER: S-EPMC12333479 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature