Associations Among Skeletal Muscle Health, Disability, and Self-Reported Physical Function in Survivors of Critical Illness: A Secondary Analysis of the Bringing to Light the Risk Factors and Incidence of Neuropsychological Dysfunction in ICU Survivors Study.

ABSTRACT:

Background

Factors associated with disability after critical illness are incompletely understood. Lower pre-existing muscle mass and muscle density on CT imaging are associated with greater mortality resulting from critical illness. Their relationship with disability and physical function in survivors of critical illness is unclear.

Research question

We sought to understand the relationship between muscle mass and muscle density before critical illness and disability and self-reported physical function after surviving a critical illness.

Study design and methods

We conducted a nested cohort study of 125 survivors of critical illness with abdominal imaging between 6 months before and 4 days after ICU admission. We measured skeletal muscle cross-sectional area at the L3

SUBMITTER: Rengel KF 

PROVIDER: S-EPMC12363371 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature