Hidden Allies: Decoding the Core Endohyphal Bacteriome of Aspergillus fumigatus.

ABSTRACT: Bacterial-fungal interactions that influence the behaviour of one or both organisms are common in nature. Well-studied systems include endosymbiotic relationships that range from transient to long-term associations. Diverse endohyphal bacteria associate with fungal hosts, emphasising the need to better comprehend the fungal bacteriome. We evaluated the hypothesis that Aspergillus fumigatus harbours an endohyphal community of bacteria that influence the host phenotype. We analysed whether 38 A. fumigatus strains show stable association with diverse endohyphal bacteria; all derived from single-conidium cultures that were subjected to antibiotic and heat treatments. The fungal bacteriome, inferred through analysis of bacterial diversity within the fungal strains (short- and long- read sequenc

SUBMITTER: Piontkivska D 

PROVIDER: S-EPMC12365344 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature