Spatial, temporal and demographic distribution characteristics of adenomyosis symptom clusters from the perspective of traditional Chinese medicine: a multicenter cross-sectional study in China from 2020 to 2022.

ABSTRACT: This study aimed to explore the differences in symptom clusters of adenomyosis (AM) patients across spatial, temporal, and age-stratified dimensions based on the theory of "Treatment in Accordance with Three Categories of Etiologic Factors". A cross-sectional study was conducted in China from 2020 to 2022, involving 1,816 AM patients. Univariate analysis, symptom co-occurrence matrices, and hierarchical clustering were used to compare clinical and symptom cluster characteristics across different latitudes (low latitude area: 691 cases vs. high latitude area: 1,125 cases), seasons (warm: 652 cases vs. cold: 473 cases), and age groups (<40 years: 895 cases vs. ≥s. years: 921 cases). AM symptom clusters exhibited significant geographical, seasonal, and age-related variations, with "Blood Stas

SUBMITTER: Wang X 

PROVIDER: S-EPMC12367498 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature