Use of Naltrexone for Patients With Stimulant Use Disorder in Malaysia: Protocol for a Retrospective Cohort Study.

ABSTRACT:

Background

Naltrexone is an opioid receptor antagonist. Naltrexone is used to block the euphoric and sedative effects of drugs such as heroin, codeine, and morphine. The medication helps to bind and block opioid receptors to decrease opioid cravings. In Malaysia, naltrexone has been used for maintenance treatments for heroin and alcohol since 1996. However, since 2011, naltrexone has been used as an off-label stimulant use disorder (StUD) treatment to achieve abstinence.

Objective

This study aims to determine the abstinence among StUD and non-StUD patients treated and without naltrexone.

Methods

We will conduct a retrospective cohort study on the effect of naltrexone or treatment as usual (TAU) by examining the data for both StUD and non-StUD patients. We will use pat

SUBMITTER: Muhamad NA 

PROVIDER: S-EPMC12371278 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature