Mitochondrial Genome and RNA Editing Tissue Specificity of <i>Centella asiatica</i>.

ABSTRACT:

Background

Centella asiatica, a medicinally important species that is rich in bioactive compounds, lacks a characterized mitochondrial genome, despite nuclear and chloroplast assemblies. We sequenced and annotated its mitochondrial genome to elucidate its genetic foundations and evolutionary mechanisms.

Methods

Assembly using Illumina short-reads and Nanopore long-reads was used to characterize the mitochondrial genome. Analyses included structural characterization, codon usage bias, repetitive sequences, horizontal gene transfer (HGT), collinearity, and phylogeny. The resulting tissue-specific (root, stem, and leaf) long non-coding RNA (lncRNA) profiles identified RNA editing sites.

Results

The complete mitochondrial genome (249,777 bp, 45.5% GC) comprises thr

SUBMITTER: Yang C 

PROVIDER: S-EPMC12385686 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature