Peripheral Vasopressor Use in Early Sepsis-Induced Hypotension.

ABSTRACT:

Importance

Evidence supporting the safety of infusing vasopressors through peripheral intravenous catheters (peripheral vasopressors) is largely derived from single-center studies, limiting generalizability.

Objective

To evaluate factors associated with vasopressor route selection and assess safety and clinical outcomes of peripheral vasopressor administration in early sepsis resuscitation.

Design, setting, and participants

This prospective cohort study is a secondary analysis of the Crystalloid Liberal vs Early Vasopressors in Sepsis (CLOVERS) trial conducted in 60 US hospitals from March 2018 to February 2022. Patients in CLOVERS who received vasopressors within 24 hours of enrollment and did not have central venous access at enrollment were included. Data were anal

SUBMITTER: Munroe ES 

PROVIDER: S-EPMC12391982 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature