Cytotransducers for Visualization of Spatiotemporal Intercellular Communication.

ABSTRACT: Visualization of intercellular communication provides a means for understanding and leveraging complicated multicellular organizations. Various nanometer-sized artifacts (nano-artifacts) can be employed as small tracers for visualization, achieving spatially and temporally controlled intervention of these small tracers in the interactions remains challenging due to their diffusion-based transportation. To achieve spatiotemporally controlled visualization, cytotransducers are conceptualized that convert veiled intra/intercellular information into visible information. A 110-mm cytotransducer is presented, composed of a lipid layer and a fluorescent nanodiamond. The designed lipid layer allows effective uptake of the cytotransducer by neutrophils, and the fluorescent nanodiamond is labeled wi

SUBMITTER: Kimura N 

PROVIDER: S-EPMC12410898 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature