Biocontrol potential of newly isolated <i>Streptomyces noursei</i> D337-11 from disease suppressive soil and its metabolites against <i>Fusarium oxysporum</i> f. sp. <i>cubense</i> in banana plants.

ABSTRACT: Banana Fusarium wilt, caused by Fusarium oxysporum f. sp. cubense, threatens global banana production. Biocontrol using Streptomyces is a promising strategy. Here, we identified Streptomyces noursei D337-11 from disease suppressive banana soils, which exhibited dual functionality in controlling F. oxysporum f. sp. cubense tropical race 4 (Foc TR4), achieving a 65.35% suppression of disease, and promoting plant growth in pot experiments. The extracts from this strain restored the soil microbiota disrupted by Foc TR4, particularly, reviving Saccharimonadales populations. Using integrated untargeted metabolomics (LC-ESIMS/MS) and genomic analysis, we identified five bioactive metabolites, including naringenin, a flavonoid l

SUBMITTER: Zhou D 

PROVIDER: S-EPMC12417419 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature