<i>Tetratricopeptide Repeat 2</i> Is a Quantitative Trait Locus That Controls Seed Size.

ABSTRACT: Seed size is a key trait affecting evolution and agronomic performance by influencing seedling establishment in natural populations and crop yields. The Arabidopsis thaliana Seed Size QTL1 (SSQ1) locus explains 10-15% of the variation in seed size. We report here that the causal gene for this locus is Tetratricopeptide Repeat Protein 2 (TPR2), which encodes a co-chaperone. Expressing TPR2 across ecotypes and genotypes showed consistent dosage effects. Each additional TPR2^Col-0 allele increased seed mass and volume by 10-14% with high reliability in Col-0, Sha, Tsu-1, and tsu2 genetic backgrounds. Reciprocal genetic crosses indicated that this locus acts maternally, consistent with female sporophytic or female gametophytic mutations. To e

SUBMITTER: Wang Z 

PROVIDER: S-EPMC12428041 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature