Discovery of new PSII inhibitors: systematic investigation for herbicidal activity screening, properties, and mode of action.

ABSTRACT:

Background

The research focused on developing effective photosystem II (PSII) inhibiting triazine-derived herbicidal compounds from the internal chemical library. Initially, the compounds were screened for their herbicidal activity using Spirodela polyrhiza (SPIPO) assays. Subsequently, compounds with stronger activity were synthesized on a gram scale and further investigated for their phytotoxicity, mobility, and mode of action.

Results

In the SPIPO screenings, two compounds, K-31706 and K-31487, showed superior efficacy at concentrations exceeding 0.4 μm, surpassing the commonly used PSII inhibition herbicide, atrazine. Both compounds showed promising performance, especially in pre-emergence applications under greenhouse conditions, with the application rate causing 50% bi

SUBMITTER: Umurzokov M 

PROVIDER: S-EPMC12441759 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature