The role of intra-abdominal pressure and point of care ultrasound to guide decongestive therapies in acute heart failure.

ABSTRACT:

Aims

Effective decongestion is crucial in managing acute decompensated heart failure (ADHF). Persistent congestion post-diuretic therapy correlates with adverse outcomes. This study evaluates whether a strategy guided by intra-abdominal pressure (IAP) and point-of-care ultrasound (POCUS) enhances decongestion compared to standard diuretic titration.

Methods and results

ABDOPOCUS-HF is a randomized, multicentre, open-label, pragmatic clinical trial involving 168 patients hospitalized with ADHF across 14 Spanish hospitals. Inclusion criteria encompass clinical signs of congestion and elevated natriuretic peptides (NT-proBNP >1000 pg/mL or BNP > 250 pg/mL). Participants are randomized 1:1 to either standard care or an intervention arm where diuretic therapy is guided by baselin

SUBMITTER: Josa-Laorden C 

PROVIDER: S-EPMC12450796 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature