Infection prevention and control measures for multidrug-resistant organisms: a systematic review and network meta-analysis.

ABSTRACT:

Background

The effectiveness of infection prevention and control measures combating multidrug-resistant organisms (MDROs) in healthcare settings remains controversial.

Methods

PubMed, Embase, MEDLINE, Cochrane Library, and CINAHL were searched from inception to June 1, 2024. The interventions encompassed standard precautions (SP), contact precautions (CP), hand hygiene (HH), environmental cleaning (ENV), antimicrobial stewardship programs (ASP), decolonization (DCL), and chlorhexidine baths (CHG). The primary outcome were the acquisition, infection, and colonization of MDROs. Secondary outcomes were all-cause mortality and MDROs-associated bacteraemia. Effect indicators were expressed as rate ratios (RRs) with 95% confidence intervals (CIs).

Results

The study included

SUBMITTER: Geng Y 

PROVIDER: S-EPMC12460372 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature