Quadrant asymmetry alteration of retinal degeneration in thyroid-associated ophthalmopathy.

ABSTRACT:

Purpose

To measure alterations in quadrant asymmetry (QA) of retinal radial peripapillary capillary (RPC) density and to determine the association between subfield alterations and thyroid-associated ophthalmopathy (TAO).

Methods

Optical coherence tomography angiography images of 51 control eyes and 80 TAO eyes were analyzed to quantify RPC density. QA was defined as the difference between the maximum and minimum RPC densities among four subfields. Comparisons of RPC QA between groups and the associations of QA with the occurrence of TAO were analyzed. Linear regression was conducted to determine the association of subfield alterations with visual field mean deviation (MD).

Results

QA of RPC density in TAO eyes was higher than in control eyes (9.58 ± 2.40 vs. 6.70 ± 2.

SUBMITTER: Liu W 

PROVIDER: S-EPMC12462272 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature