The Majority of <i>Bacillus subtilis</i> Strains Isolated From Blood Cultures Were Derived From Traditional Japanese Fermented Soybeans Natto: A Single-center Retrospective Study.

ABSTRACT:

Background

Natto consumption has been associated with improved cardiovascular and survival outcomes. Bacillus subtilis variant natto (B. subtilis var. natto) is essential for soybean fermentation in natto production. Recently, several cases of B. subtilis var. natto bacteremia have been reported, although the contribution of B. subtilis var. natto remains unclear. This study assessed the prevalence and clinical impact of B. subtilis var. natto in B. subtilis bacteremia.

Methods

This retrospective cohort study analyzed medical records of patients with positive B. subtilis blood cultures at Tenri Hospital from 1 April 2016 to 31 March 2023. True bacteremia required portal-of-entry or, for intra

SUBMITTER: Sada RM 

PROVIDER: S-EPMC12464813 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature