Immune Enhancement Effects and Extraction Optimization of Polysaccharides from <i>Peristrophe roxburghiana</i>.

ABSTRACT: The present study aims to optimize the extraction process and systematically investigate the bioactivity of polysaccharides derived from Peristrophe roxburghiana (Schult.) Brem. (CPPRs). To this end, the Box-Behnken design-response surface methodology was employed to optimize the extraction parameters of polysaccharides. The optimal extraction conditions were as follows: extraction temperature, 84 °C; extraction duration, 208 min; liquid-to-material ratio, 1:27 g/mL; extraction times, 4 times. The maximum extraction yield reached 17.89%, and the yield under non-optimal extraction conditions is 11-16%. This study systematically investigated the polysaccharides' physicochemical, structural, and morphological properties using multiple advanced techniques (FTIR, SEM, XRD, HPLC, rheology

SUBMITTER: Chen Y 

PROVIDER: S-EPMC12466801 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature