Decoding TRIP13's Role in Gastric Cancer: Implications for Prognosis and Immune Response.

ABSTRACT: Background/Objectives: Gastric cancer (GC), a prevalent global malignancy and a leading cause of cancer-related mortality, has a poorly understood prognosis related to TRIP13 expression. TRIP13 has a recognized part in driving tumor progression across different cancer types, yet its precise role in GC remains beyond our full comprehension. Our study aimed to explore TRIP13's prognostic value and function in GC patients. Methods: We extensively explored TRIP13's influence on GC prognosis, functionality, and immune response by examining various cancer-related databases like UALCAN, GEPIA, GEO, and TIMER. Immunohistochemistry (IHC) staining was also conducted to assess the link between TRIM13 and GC patient survival. Results: TRIP13</

SUBMITTER: Shi T 

PROVIDER: S-EPMC12467871 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature